The Mean Corpuscular Hemoglobin (MCH) blood test is a vital component of a complete blood count (CBC), which provides essential information about the health of our blood cells. MCH specifically focuses on red blood cells (RBCs) and helps healthcare professionals evaluate the amount of hemoglobin within each RBC.

This page discusses the MCH blood test, its relevance, normal range values, probable reasons of aberrant findings, and the necessity of interpreting MCH in combination with other CBC parameters.

What is the MCH In Blood Test?

The MCH blood test low measures the average amount of hemoglobin, the oxygen-carrying protein within red blood cells, in a given blood volume. It is usually performed as part of a CBC. This routine blood test provides valuable information about different components of our blood, including red blood cells, white blood cells, and platelets. MCH, along with other CBC parameters, aids in diagnosing and monitoring various health conditions.

Understanding MCH Results:

  • MCH results are reported in picograms (pg) and represent the average amount of hemoglobin per red blood cell. The normal range for MCH can vary slightly depending on the laboratory but generally falls between 27 and 33 pg. Values below or above this range may indicate potential health concerns and require further investigation.
  • Low MCH Levels (Microcytic Anemia): A decrease in MCH values may suggest microcytic anemia, a condition characterized by smaller-than-normal red blood cells. Causes of low MCH include iron deficiency anemia, thalassemia, chronic diseases, and certain genetic disorders.
  • High MCH Levels (Macrocytic Anemia): Elevated MCH values may indicate macrocytic anemia, in which red blood cells are larger than normal. Common causes of high MCH include vitamin B12, folate, certain medications, alcohol abuse, and some types of anemia.

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Interpreting MCH in Context:

  • While MCH is a valuable indicator of red blood cell health, it is crucial to interpret its results in conjunction with other CBC parameters to comprehensively understand the underlying condition. Key parameters to consider include:
  • Hemoglobin (Hb) Level: Hemoglobin is the protein that carries oxygen in red blood cells. Evaluating MCH to hemoglobin levels provides additional insights into the oxygen-carrying capacity of the blood.
  • MCV (mean corpuscular volume): MCV is a measurement of the average size of red blood cells. Combining MCH with MCV allows for more accurate diagnosis of microcytic anemia (low MCV) and macrocytic anemia (high MCV).
  • Red Blood Cell Count (RBC): RBC count determines the number of red blood cells per blood volume. Assessing MCH alongside RBC count aids in diagnosing and monitoring conditions related to red blood cell production and destruction.
  • Other CBC Parameters: White blood cell count (WBC) and platelet count are essential components of a complete blood count. Examining MCH alongside these parameters can provide a comprehensive picture of an individual’s overall blood health.

Causes of Abnormal MCH Results:

  • Abnormal MCH values can be indicative of various underlying conditions. Here are some common causes:
  • Anaemia: Low MCH may cause iron deficiency, thalassemia, and chronic illness anaemia. Vitamin B12, folate, and some kinds of anaemia may cause high MCH.
  • Nutritional Deficiencies: Iron, vitamin B12, and folate deficiencies may damage red blood cells and cause aberrant MCH findings.
  • Chronic Diseases: Chronic conditions like kidney disease, liver disease, and autoimmune disorders can influence red blood cell production, leading to changes in MCH levels.
  • Medications and Treatments: Some medications, such as chemotherapy drugs or certain anticonvulsants, can impact red blood cell health and contribute to abnormal MCH values.
  • Inherited Disorders: Genetic conditions, including thalassemia and sickle cell disease, can affect red blood cell structure and function, resulting in abnormal MCH levels.

Follow-up and Treatment:

If MCH levels fall outside the normal range, further investigation is necessary to determine the underlying cause. Additional tests, such as iron studies, vitamin B12, folate levels, peripheral blood smear examination, or bone marrow evaluation, may be conducted to aid in diagnosis and guide appropriate treatment.

Treatment options for abnormal MCH values depend on the underlying condition. They may involve dietary modifications, iron or vitamin supplementation, blood transfusions, medication adjustments, or management of the underlying disease.

Importance of Regular Blood Tests:

Preventive healthcare requires routine blood testing, including the MCH test. Regular checkups enable healthcare practitioners to monitor MCH levels, identify any irregularities, and take necessary action to preserve blood health.


The Mean Corpuscular Hemoglobin (MCH) blood test is a valuable component of a complete blood count, providing insights into red blood cell health. Interpreting MCH results in the context of other CBC parameters allows for a comprehensive understanding of an individual’s blood profile. 

Abnormal MCH values can indicate underlying conditions, including anemia, nutritional deficiencies, chronic diseases, and genetic disorders. Proper follow-up and treatment, guided by additional diagnostic tests, help address the underlying cause and restore red blood cell health. Regular blood tests, including the MCH blood test, are essential for proactive healthcare and early detection of potential health concerns related to red blood cell function.